Increased
consumption of omega-3 fats is widely promoted globally because of a common
belief that it will protect against, or even reverse, diseases such as cancer,
heart attacks and stroke.
But two systematic reviews published recently find that
omega-3 supplements may slightly reduce coronary heart disease death and
events, but slightly increase risk of prostate cancer.
Both beneficial and harmful effects are small.
If 1,000 people took omega-3 supplements for around four
years, three people would avoid dying from cardiovascular (heart) disease, six
people would avoid a coronary event (such as a heart attack) and three extra
people would develop prostate cancer.
The systematic reviews were published in the British
Journal of Cancer and the Cochrane Database of Systematic
Reviews respectively.
Omega-3 is a type of fat. Small amounts are essential for
good health and can be found in the food that we eat, including nuts, seeds and
fatty fish such as salmon.
Omega-3 fats are also readily available as
over-the-counter supplements, and they are widely bought and used.
The research team looked at 47 trials involving adults
who didn’t have cancer, who were at increased risk of cancer or who had a previous
cancer diagnosis, and 86 trials with evidence on cardiovascular events or
deaths.
More than 100,000 participants were randomised to consume
more long-chain omega-3 fats (fish oils) or maintain their usual intake, for at
least a year for each of the reviews.
They studied the number of people who died; received a
new diagnosis of cancer, heart attack or stroke; and/or died from any of the
diseases.
Lead author Dr Lee Hooper, from the University of East
Anglia’s Norwich Medical School in the United Kingdom, said: “Our previous
research has shown that long-chain omega-3 supplements, including fish oils, do
not protect against conditions such as anxiety, depression, stroke, diabetes or
death.
“These large systematic reviews included information from
many thousands of people over long periods.
“This large amount of information has clarified that if
we take omega-3 supplements for several years, we may very slightly reduce our
risk of heart disease, but balance this with very slightly increasing our risk
of some cancers.
“The overall effects on our health are minimal.
“The evidence on omega-3 mostly comes from trials of fish
oil supplements, so health effects of oily fish, a rich source of long-chain
omega-3, are unclear.
“Oily fish is a very nutritious food as part of a
balanced diet, (it is) rich in protein and energy, as well as important
micronutrients such as selenium, iodine, vitamin D and calcium – it is much
more than an omega-3 source.
“But we found that there is no demonstrable value in
people taking omega-3 oil supplements for the prevention or treatment of
cancer.
“In fact, we found that they may very slightly increase
cancer risk, particularly for prostate cancer.
“However this risk is offset by a small protective effect
on cardiovascular disease.
“Considering the environmental concerns about industrial
fishing and the impact it is having on fish stocks and plastic pollution in the
oceans, it seems unhelpful to continue to take fish oil tablets that give
little or no benefit.”
The research was funded by the World Health Organization
(WHO).
Tags
Nutrition